CVE-2026-31968

HTSlib CRAM decoder vulnerable to buffer overflow

State
Published
Severity
8.8 High
Published
Mar 18, 2026
Updated
Mar 18, 2026
Reserved
Mar 10, 2026

Read the record on cve.org

Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. For the `VARINT` and `CONST` encodings, incomplete validation of the context in which the encodings were used could result in up to eight bytes being written beyond the end of a heap allocation, or up to eight bytes being written to the location of a one byte variable on the stack, possibly causing the values to adjacent variables to change unexpectedly. Depending on the data stream this could result either in a heap buffer overflow or a stack overflow. If a user opens a file crafted to exploit this issue it could lead to the program crashing, overwriting of data structures on the heap or stack in ways not expected by the program, or changing the control flow of the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Scores

CVSSScoreVectorSource
4.08.8 HighCVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:N/VI:H/VA:L/SC:N/SI:N/SA:NGitHub_M

Weaknesses

  • CWE-121 Stack-based Buffer Overflow
  • CWE-122 Heap-based Buffer Overflow
  • CWE-787 Out-of-bounds Write
  • CWE-843 Access of Resource Using Incompatible Type ('Type Confusion')

Affected Products

ProductVersions
htslibsamtools
  • < 1.21.1Affected
  • >= 1.22, < 1.22.2Affected
  • = 1.23Affected

References

Every record here comes from the CVE Program’s CVE List. © 1999–2026 The MITRE Corporation. CVE is a registered trademark of The MITRE Corporation. The records are reproduced under the CVE Program terms of use.